KLHDC1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002784
Fusion event
HBV-KLHDC1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr14
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
50207046/49740328 (Hg38)
End
50207046/49740328 (Hg38)
Location type
Intronic
Target gene
KLHDC1
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-208a/Upstream/1979224; hsa-mir-1185-1/Downstream/226071;
Nearest TSS
ENST00000550708/Upstream/14720; ENST00000553703/Downstream/27280;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/46622, chr14-CpG: 82/Downstream/27802
Upstream sequence
TTCACACTAAATGGCTATTCAGCAAGAATGTTGATATTCTAACATTGCAAAATATGAAGGGCCTGAAATGTTACTCTGTGGTTTAATTAATCTTCAGGAT
Downstream sequence
GACTGGCttttttgtttgtttgtttttgagatggagtcttgctctgtcccccaggctggagtgcagtggtgcgatctcggctcactgcaagctctgcctc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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