Basic Information
VIS ID
TVIS10002795
Fusion event
HBV-chr2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
133022658/132265085 (Hg38)
End
133022658/132265085 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA2S
Target gene
ANKRD30BL ; MIR663B
Nearest miRNA
hsa-mir-1285-2/Upstream/8005; hsa-mir-10b/Downstream/168626;
Nearest TSS
ENST00000437798/Upstream/7116; ENST00000622084/Downstream/29292;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/6918, chr2-CpG: 79/Downstream/87658
Upstream sequence
cacaccactgcactccagccagggcgagggacagagcaagactccctctcagaaacaaaCACACAAAGCCAATAAAGATGTTAAGGTGTTTAACTCAACG
Downstream sequence
TGTCAGGCTCAGGTCTCTTGACAGGATACATCCAGCACCCGGGGAAACGTCGAGGGGTGGGGTGGAATCTATTTTGTGGCCTCAAGGAAGGGTTTGAAAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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