Basic Information
VIS ID
TVIS10002838
Fusion event
HBV-chr3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q27.1
Reference genome
GRCh37/hg19
Start
184317497/184599709 (Hg38)
End
184317497/184599709 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA3C
Nearest miRNA
hsa-let-7g/Upstream/358220; hsa-mir-1248/Downstream/653501;
Nearest TSS
ENST00000440867/Upstream/19961; ENST00000610001/Downstream/112293;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/15363, chr3-CpG: 44/Downstream/1879
Nearby gene
EPHB3(-17301) ; MAGEF1(+110658) ;
Nearest cancer related gene
EPHB3(TSG, -17301) ;
Upstream sequence
tctatgcgatgattccattccattccattggaagatgattccattcgagaccattcgatgattgcattcaattcattcgatgacgattccattcaattcc
Downstream sequence
CACTTTCGCCCATATCAGCTGGGCCCTCCAGGACAGACTGGGCAGTCCACCGTTGGGGGAAGGCTGAAGATCCACTATGGAATCACAGATGGCGTGTGGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate