Basic Information
VIS ID
TVIS10002845
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
61401139/60935467 (Hg38)
End
61401139/60935467 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1B
Nearest miRNA
hsa-mir-12136/Upstream/1202171; hsa-mir-101-1/Downstream/910608;
Nearest TSS
ENST00000473358/Upstream/67469; ENST00000496712/Downstream/17382;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/861599, chr1-CpG: 86/Downstream/107503
Nearby gene
C1orf87(-861697) ; NFIA(+141807) ;
Upstream sequence
AGTCCATTCTGTGGGCCCAGCATCGCGTGATCTCCACACTCACTGCCATCTGTTTCCTATCAAGGCTGAACACAAGCTCGTGCGTGTGGTCACAATTGCA
Downstream sequence
CAGAAAAATCACTCGGCCAACAAATATGGAAATGTCAGCTTCAttctctctctctttctctctctctttctctttctctgtctctctctctctctctcac
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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