Basic Information
VIS ID
TVIS10002858
Fusion event
HBV-LOC105372085 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
39461035/41881070 (Hg38)
End
39461035/41881070 (Hg38)
Location type
Intronic
Target gene
LOC105372085
Nearest miRNA
hsa-mir-1-2/Upstream/2204291; hsa-mir-122/Downstream/3089012;
Nearest TSS
ENST00000575820/Upstream/248885; ENST00000590220/Downstream/74136;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/2039205, chr18-CpG: 180/Downstream/2797948
Nearby gene
KC6(-360474) ; PIK3C3(+74164) ;
Upstream sequence
ACACCTGCCAAGTGCGATATACAGATAATGAAAGTCAGGAGAATTCAGGAtaggagttcaagggaagactttccagaaaagatggaaatttgatctatgc
Downstream sequence
tttaaagaatttaggaagatagaaaggaaaatgagggcattccaggtaAGATGATATATAAGAGTATAAGCCAGTTTCAAGGGGTAGAGACGATCAATTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate