VISDB Viral Integration Site DataBase

VIS ID

TVIS10002885

Fusion event

HBV-PPFIA1 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr11

Cytoband

q13.3

Reference genome

Start

End

70203275/70357169 (Hg38)

Location type

Intronic

Fragile sites / regions

FRA11H ; FRA11A

Target gene

miRNAs that regulate target gene

hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-142-3p

Nearest miRNA

hsa-mir-10392/Upstream/73099; hsa-let-7a-2/Downstream/515101;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/85778, chr11-CpG: 79/Downstream/41013

Upstream sequence

GTGCCCAAGTGAGCCAACAAATGTAGAACAAAACTAAACCCAGTTCTGCAATAAAATAGGCAGTTTGTGTAGTCCATGGGATAAGGGCTGAGCTTGAGCA

Downstream sequence

ATGTGGAAGATGGTAATGCCAGGCTTACAGGGTGAAACTTGACGGGCTGTATGATGACTGTGACTGTGGGAAAAATCATCTGGCCACTTTTAAGTGCCCT

Target sequence

CCAGAGGTGAAGAACAGGCAGCAATTTATAGAAAGTCTTTGATAGGCAATAATGGAGACCAATTAACATACCTCCCCCAGAAGGCAAAAAACTGAAGGtattaagaaaataattttcaaaacttggaaataagaccaaaaaatgcctgtatgttttttaaatgtcatattggagaataatctgagaagtctgcctagacgtcatctgttattcagggacttctaactttgcttgacttattattggttttgattt