Basic Information
VIS ID
TVIS10002946
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
1107728/1113940 (Hg38)
End
1107728/1113940 (Hg38)
Location type
Promoter;downstream
Target gene
RNF212 ; TMED11P
Nearest miRNA
hsa-mir-571/Upstream/763688; hsa-mir-12113/Downstream/872444;
Nearest TSS
ENST00000502981/Upstream/301; ENST00000510332/Downstream/18369;
Nearest CpG islands
chr4-CpG: 97/Target, None/Upstream, None/Downstream
Upstream sequence
CTAAGTCCAACAGAGCATAAAGACAGAAAAAAAAAAAAGAAGAAAGGTAAGATCTGGGACAGTGACGCGGGAAGGACAGGGAATGGAAGAGAGGTAATGA
Downstream sequence
AGGCAGGGGAGGAGTAGGGGAGAGTGGGCGTGGGGGCCCTGGGGGCCCGGGGAGCGGGATAGGAGGGAGGGAGGGATAAgtgggtgtgggagttggggtg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate