Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene1171694105625011135621113639113297710812901083102109967311007631113800111400110729531073082111354211136011113972
Basic Information
VIS ID
TVIS10002947
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
1107760/1113972 (Hg38)
End
1107760/1113972 (Hg38)
Location type
Promoter;downstream
Target gene
RNF212 ; TMED11P
Nearest miRNA
hsa-mir-571/Upstream/763720; hsa-mir-12113/Downstream/872412;
Nearest TSS
ENST00000502981/Upstream/333; ENST00000510332/Downstream/18337;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/32, chr4-CpG: 131/Downstream/30238
Upstream sequence
aaaacaattacttcacccaaaaagttatctaatgatgctcctttatagtcaaaacctcctgtcacttttgacacctggaaatcactgctctgttttctat
Downstream sequence
GGGGCCCTGGGGGCCCGGGGAGCGGGATAGGAGGGAGGGAGGGATAAgtgggtgtgggagttggggtgggagcgggagtggggatgtgggagttggggtg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate