NLRP13 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002967
Fusion event
HBV-NLRP13 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
GRCh37/hg19
Start
56407216/55895850 (Hg38)
End
56407216/55895850 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
NLRP13
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7e/Upstream/507608; hsa-mir-10394/Downstream/2438838;
Nearest TSS
ENST00000633603/Upstream/37153; ENST00000590542/Downstream/36461;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/37547, chr19-CpG: 178/Downstream/190822
Nearby gene
NLRP4(-13996) ; NLRP13(+95) ;
Upstream sequence
ccaatgatgagatgccgctcgtggctacacagcaggtgcacagcacagagatcactcccacccttactggaagttccgttggCCTGCATGGCCTGAGGAA
Downstream sequence
GCCGAGTGCAATGGAAACCTGACACATGCTCTAGAAGCCTAGTCAATCTAGCCTTGTCCCTGTATGTTCTCCCCTGCAGAAAAGTCAGTGAGGTTTACCC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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