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VISDB
Viral Integration Site DataBase
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TVIS10002989
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002989
Fusion event
HBV-OSTM1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
108371620/108050416 (Hg38)
End
108371620/108050416 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA6F
Target gene
OSTM1
miRNAs that regulate target gene
hsa-mir-140-5p
;
hsa-mir-374b-5p
;
hsa-mir-106b-5p
;
hsa-mir-125a-5p
;
hsa-mir-26b-5p
;
hsa-let-7b-5p
;
hsa-mir-6083
;
hsa-mir-155-5p
;
hsa-mir-5579-3p
;
hsa-mir-6882-3p
;
hsa-mir-208b-5p
;
hsa-mir-208a-5p
;
hsa-mir-4796-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-93-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-526b-3p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-106a-5p
;
hsa-mir-520c-3p
;
hsa-mir-520d-3p
;
hsa-mir-520e
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-520b
;
hsa-mir-302e
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-520f-3p
;
hsa-mir-6818-3p
;
hsa-mir-6873-3p
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-6798-3p
;
hsa-mir-593-3p
;
hsa-mir-6895-3p
;
hsa-mir-942-5p
;
hsa-mir-1236-3p
;
hsa-mir-6515-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-5695
;
hsa-mir-519d-5p
;
hsa-mir-5699-3p
;
hsa-mir-4421
;
hsa-mir-6748-3p
;
hsa-mir-660-3p
;
hsa-mir-4667-3p
;
hsa-mir-6887-3p
;
hsa-mir-5195-5p
;
hsa-mir-106a-3p
;
hsa-mir-138-1-3p
;
hsa-mir-200b-3p
;
hsa-mir-200c-3p
;
hsa-mir-217
;
hsa-mir-328-5p
;
hsa-mir-369-3p
;
hsa-mir-410-3p
;
hsa-mir-429
;
hsa-mir-4418
;
hsa-mir-509-3-5p
;
hsa-mir-509-5p
;
hsa-mir-6795-5p
;
hsa-mir-6807-3p
;
hsa-mir-6835-5p
;
hsa-mir-6881-5p
;
hsa-mir-6885-5p
;
hsa-mir-6887-5p
;
hsa-mir-7109-5p
;
hsa-mir-8084
;
hsa-mir-129-5p
;
hsa-mir-149-5p
;
hsa-mir-3064-5p
;
hsa-mir-3672
;
hsa-mir-4524a-3p
;
hsa-mir-4794
;
hsa-mir-624-3p
;
hsa-mir-6504-5p
;
hsa-mir-664a-5p
;
hsa-mir-6822-3p
;
hsa-mir-6864-3p
;
hsa-mir-760
;
hsa-mir-8055
;
hsa-mir-8057
Nearest miRNA
hsa-mir-10398/Upstream/1266196; hsa-mir-1202/Downstream/11018631;
Nearest TSS
ENST00000381078/Upstream/748;
ENST00000426008/Downstream/650;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/91916
,
chr6-CpG: 97/Downstream/23812
Upstream sequence
CAACATTTTCTTGGGAAAGCAAGATGAGTGGCTTTGCAATGATTAATTCTTCACGAGAGAGAGAGGGGAAGTTGTGACTTGCTGTGTATGTGTGTGCACA
Downstream sequence
gcactggcacgatctcagctcactgcaacctctccctcccggtttcaagcgattctcctgcctcagcctcctgaatagctgggataacaggcgtgtgcca
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Sample Information
×
Sample name
084013T
Sample type
Tumor
Gender
Female
CpG Island Information
×
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