DHX32 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002992
Fusion event
HBV-DHX32 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr10
Cytoband
q26.2
Reference genome
GRCh37/hg19
Start
127555687/125867118 (Hg38)
End
127555687/125867118 (Hg38)
Location type
Exonic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
DHX32
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-107/Upstream/47296; hsa-mir-202/Downstream/3976181;
Nearest TSS
ENST00000439456/Upstream/12259; ENST00000494896/Downstream/14197;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/43490, chr10-CpG: 152/Downstream/28562
Upstream sequence
CTCGAAAGGGATCACGTAGCCAACCTCATGACCAATGTTAACATCCATTTCATCCGCCACCCGCAGGGCGAGCTGGACCACAGTCTGCTTGTGGACCTGT
Downstream sequence
GTGCATATCACGCCCCCGTGCTGGTAGTGGATGGAAAGACAATATTCAGCACACCACTGAGGAACCTGTAGCAGGAAAAAATGAGACAGGATCAGCTTCT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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