Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10002994
Fusion event
HBV-AHI1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q23.3
Reference genome
End
135611443/135290305 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-218-5p ; hsa-mir-619-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-6814-5p ; hsa-mir-4761-5p ; hsa-mir-6504-3p ; hsa-mir-3159 ; hsa-mir-4735-3p ; hsa-mir-4438 ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-331-5p ; hsa-mir-636 ; hsa-mir-3618 ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-1283 ; hsa-mir-455-5p ; hsa-mir-4678 ; hsa-mir-4517
Nearest miRNA
hsa-mir-10398/Upstream/51049; hsa-mir-1202/Downstream/3144908;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/107032, chr6-CpG: 84/Downstream/207058
Nearest cancer related gene
AHI1(OG, No orient, 0)
Upstream sequence
ATTAAACCAAGATAAAGGGATTCTGACAGAACAGTACACATTTCTGGAACTTCCCTCAGGGTCTTGAACGACAAGCCTAAGTTGACTTTCTCCATGTAAT
Downstream sequence
gacttgtcagtccttattttacttgcctctctctggtatttgtccttgctgaccatgctttcctaaatcttttcctgttgacaacatagcgcaactttct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.