L3MBTL4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003004
Fusion event
HBV-L3MBTL4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
5972976/5972977 (Hg38)
End
5972976/5972977 (Hg38)
Location type
Intronic
Target gene
L3MBTL4
miRNAs that regulate target gene
hsa-let-7b-5p
Nearest miRNA
hsa-mir-3976/Upstream/132144; hsa-mir-1-2/Downstream/401384;
Nearest TSS
ENST00000575820/Upstream/16876; ENST00000577935/Downstream/52114;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/76727, chr18-CpG: 22/Downstream/311398
Nearest cancer related gene
L3MBTL4(TSG, No orient, 0)
Upstream sequence
agaatagaacagaagagaatagaatagaatagaatagaatagaatagaatagaatagaatagaatagaatagaatagaatagaatagaatagaatagaaC
Downstream sequence
GGAGTAAGAGCAAAACTTATACCTCATTGAGTTgtgatttggacagctcctggtacataacgtgttcaatacatgtcagatattatGTTACTGTTACAAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate