Basic Information
VIS ID
TVIS10003005
Fusion event
HBV-chr18 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
8885691/8885693 (Hg38)
End
8885691/8885693 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-3976/Upstream/2511268; hsa-mir-1-2/Downstream/1873891;
Nearest TSS
ENST00000575820/Upstream/55770; ENST00000497577/Downstream/216937;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/100047, chr18-CpG: 58/Downstream/216725
Nearby gene
MTCL1(-52916) ; NDUFV2(+216937) ;
Upstream sequence
ctgtgaagaaagtcattggtagcttgatggggatgtcattgaatctataaatcaccttgggcagtatggccattttcacaatattgattcttcctatctg
Downstream sequence
tgagcatggaatgttcttccatttgtttgtgccctcttttattttgttgagcagtagtttgttgttctccttgaagaggtccttcacatcccttgtaagt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate