Basic Information
VIS ID
TVIS10003026
Fusion event
HBV-chr9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
137492775/134600929 (Hg38)
End
137492775/134600929 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7a-1/Upstream/221457; hsa-mir-126/Downstream/248369;
Nearest TSS
ENST00000422679/Upstream/48191; ENST00000464187/Downstream/40845;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/8731, chr9-CpG: 91/Downstream/40736
Nearby gene
RXRA(-160344) ; COL5A1(+40876) ;
Upstream sequence
atttccttgtggtcagagaatgtggtttgtatgatatccatccttaaaaagttttttctttttgttattggttacagcagcaacaggaaaaaacattttt
Downstream sequence
TGGTGGCCTGGAGCAGAAAGAGCCCCATCACCCGCCCTCTGGCTTTTCCAGCTTCCCATAGTTAACTGTCAGCGACCATGGAGCGCCCAGGGCAGAGTCC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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