Basic Information
VIS ID
TVIS10003088
Fusion event
HBV-chr3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr3
Cytoband
q25.33
Reference genome
GRCh37/hg19
Start
159358050/159640261 (Hg38)
End
159358050/159640261 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
IQCJ-SCHIP1 ; SCHIP1
miRNAs that regulate target gene
hsa-mir-98-5p
Nearest miRNA
hsa-let-7g/Upstream/357527; hsa-mir-1224/Downstream/764327;
Nearest TSS
ENST00000440867/Upstream/366506; ENST00000639448/Downstream/123452;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/837721, chr3-CpG: 166/Downstream/122896
Upstream sequence
ATGCAATGGAAGGTATCAGTGAAGATTAATCTGAGGGGCAGTGTTATTATCTGAGAGAACAGTTCAAATTAATTATAGTTGTCACTTCCCATAACTCAAC
Downstream sequence
AGTTATCTGAGCTATGAGGTACAAATGAGAAATTGAGGTGCTCTAATCCTGATTCTACCAGCAACTGTGTATGATAGATCTGCAAATCCTTTCTCAGAGT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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