Basic Information
VIS ID
TVIS10003092
Fusion event
HBV-chr19 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
77668/77668 (Hg38)
End
77668/77668 (Hg38)
Location type
ncRNA_exonic
Fragile sites / regions
FRA19B
Target gene
FAM138A ; FAM138F
Nearest miRNA
hsa-mir-1302-11/Upstream/5558; hsa-let-7e/Downstream/727272;
Nearest TSS
ENST00000633603/Upstream/9; ENST00000318050/Downstream/18;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/6324, chr19-CpG: 70/Downstream/189417
Upstream sequence
CTCTGTAGGGTGAGAAAGGGAGGCTAAAGCCTGGTGCCCACTGCCCTGGCTGCTCCGCATTGCAGGAGCTGCGCCCTTCCTTTCCTGGCACAGGGTCCAC
Downstream sequence
AGCCCCGAAACCCCGTTGTGTGGGAGCTGGGCACAGGGCAGCAGGACTAATCCTTGGAACAGCTCAGGGAGGATTATCCCAGCCACTGTCAGCAGCGGTG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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