Basic Information
VIS ID
TVIS10003097
Fusion event
HBV-ZNF729 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr19
Cytoband
p12
Reference genome
GRCh37/hg19
Start
22486366/22303564 (Hg38)
End
22486366/22303564 (Hg38)
Location type
Intronic
Target gene
ZNF729
Nearest miRNA
hsa-mir-10395/Upstream/1904210; hsa-let-7e/Downstream/12819136;
Nearest TSS
ENST00000633603/Upstream/17156; ENST00000599129/Downstream/118782;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/16679, chr19-CpG: 69/Downstream/214030
Upstream sequence
AGCACAAAAAATGTACATGTTTGTTATCATGCCATTAGTTTTATACTTTATTATCCAGAAAGGTATCTTATCTACACTGGTGTTGCGGATCTTATGCCAT
Downstream sequence
TCTTTTTTCTCAGAATTTGAGACTACATTAGATAATATTTCTGTGTTGAAAATTATTTTATTGGATATGTTCGGTCATCCCTATAAGTTAGAATCTGTTC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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