Basic Information
VIS ID
TVIS10003104
Fusion event
HBV-FAM138B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
114334982/113577405 (Hg38)
End
114334982/113577405 (Hg38)
Location type
ncRNA_exonic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
FAM138B
Nearest miRNA
hsa-mir-1285-2/Upstream/1806271; hsa-mir-10b/Downstream/5554;
Nearest TSS
ENST00000437798/Upstream/23; ENST00000476236/Downstream/49824;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/22792, chr2-CpG: 110/Downstream/6319
Upstream sequence
CCGCTGCTGACAGTGGCTGGGATAATCCTCCCTGAGCTGTTCCAAGGATTAGTCCTGCTGCCCTGTGCCCAGCTCCCACACAACGGGGTTTCGGGGCTGT
Downstream sequence
GGACCCTGTGCCAGGAAAGGAAGGGCGCAGCTCCTGCAATGCGGAGCAGCCAGGGCAGTGGGCACCAGGCTTTAGCCTCCCTTTCTCACCCTACAGAGGG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate