Basic Information
VIS ID
TVIS10003106
Fusion event
HBV-chr1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
255427/285676 (Hg38)
End
255427/285676 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-1302-2/Upstream/97718; hsa-mir-101-1/Downstream/346939;
Nearest TSS
ENST00000473358/Upstream/125230; ENST00000412666/Downstream/73181;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/85555, chr1-CpG: 99/Downstream/83116
Nearby gene
LOC729737(-114861) ; LOC100133331(+68465) ;
Upstream sequence
GAATTACTCAAGTCTTAGAAGCACCACTTGTCTTTTTTCAAGGGAGAGAAATGCTCAAGTGATGGGCTGAAGTGAAGGGAGGGAGTCACTCACTTGAATG
Downstream sequence
GTTCCCTTAGGCTGTGTGGATGCAAACAGCATTAGACAATGACACTGACAGTGGGAAATGCACTGGAGACGATGATTGGCAAAGCCCTCCTTTTCTCCCC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate