AXIN1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003107
Fusion event
HBV-AXIN1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
403697/353697 (Hg38)
End
403697/353697 (Hg38)
Location type
Promoter
Target gene
AXIN1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-320c ; hsa-mir-769-3p ; hsa-mir-484 ; hsa-mir-320a ; hsa-mir-92a-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-6859-4/Upstream/336578; hsa-mir-11401/Downstream/181619;
Nearest TSS
ENST00000527434/Upstream/1024; ENST00000454619/Downstream/16106;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/234, chr16-CpG: 99/Downstream/6287
Nearest cancer related gene
AXIN1(TSG, No orient, 0)
Upstream sequence
CCAATATATGGTGGCTCTCACCCGGACAGGAGCCACAACCTCCAAAGAGCCCACCGGCTAGGACCCTCTGCCTTGATTTCTCCCAGGCACCATCTAGTAT
Downstream sequence
CAGAGAAGGGTTCTCCTTCCCTCCGCTGCCCAGGCCAGCCCGAGAGCAAGGCCATTGGAGTGTCCAGACCCCTGCACCCCTTCCCCTGGGCTGTCTCCAC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate