BMP6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003110
Fusion event
HBV-BMP6 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
7742003/7741770 (Hg38)
End
7742003/7741770 (Hg38)
Location type
Intronic
Target gene
BMP6
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-22-3p
Nearest miRNA
hsa-mir-3691/Upstream/1572335; hsa-mir-10398/Downstream/2697947;
Nearest TSS
ENST00000381078/Upstream/14973; ENST00000645232/Downstream/147191;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/12895, chr6-CpG: 170/Downstream/168084
Upstream sequence
tcccagctactcaggaggctaaagcaggagaatcgcttgaacctgagaggcagaggttgcagtgagctgagattgtgccgttgtactatggcctgggcga
Downstream sequence
GAGCTGCATGAGGCTTCAACGAAGGAGTTGGAGGTCTGAAGTTCCAGCGTTGGCTCTGCTACCCCTCAGCTGTGGGATTTGGTGAATCACCTTCAACACT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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