Basic Information
VIS ID
TVIS10003113
Fusion event
HBV-chr15 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
20120731/19915478 (Hg38)
End
20120731/19915478 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10393/Downstream/917317;
Nearest TSS
ENST00000557528/Downstream/49623;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/16030, chr15-CpG: 170/Downstream/27962
Nearby gene
CHEK2P2(+367266) ;
Upstream sequence
ATGTGCTGGCATCGCTGGGATGATTTTCTCACACTACATGAATAATATCTACAGACTTCGTGAATATGAGCCACTTGCATAGAGTTAAAGTAGGCATCTC
Downstream sequence
TTTGCTGGGAAATTTATCAAATGGGAGTATGAAGTGTTTTTAAAAGATACTTGTTTGTTTGTAGCTGGTAGGTCTACAGTGGCTCATGGCAATGGTTGAG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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