PABPC3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003119
Fusion event
HBV-PABPC3 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr13
Cytoband
q12.13
Reference genome
GRCh37/hg19
Start
25660843/25086705 (Hg38)
End
25660843/25086705 (Hg38)
Location type
Promoter
Target gene
PABPC3
miRNAs that regulate target gene
hsa-mir-149-5p ; hsa-mir-10a-5p ; hsa-mir-423-3p ; hsa-mir-8088 ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-561-3p ; hsa-mir-3973 ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-6841-3p ; hsa-mir-3200-3p ; hsa-mir-587
Nearest miRNA
hsa-mir-2276/Upstream/924201; hsa-mir-1267/Downstream/14577329;
Nearest TSS
ENST00000623511/Upstream/163816; ENST00000281589/Downstream/9163;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/17285, chr13-CpG: 48/Downstream/9198
Upstream sequence
ctgtaattccagcactttgagaggctaagatgagaggattgcttaagaccaggatttgaaaccagcctgggcaacatagtgagaccccatctctacaaaa
Downstream sequence
aaaatttcaaaattagctggatatggtggtgcacacctgtagtcccagctactcgggaggctgaagttggagggtcactggagcctgggagttggaggct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate