Basic Information
VIS ID
TVIS10003131
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
59817037/58951319 (Hg38)
End
59817037/58951319 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA4B
Nearest miRNA
hsa-mir-12113/Upstream/6238572; hsa-mir-1243/Downstream/1971300;
Nearest TSS
ENST00000502981/Upstream/386197; ENST00000513836/Downstream/25778;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1755370, chr4-CpG: 222/Downstream/2248846
Nearby gene
IGFBP7-AS1(-1745572) ;
Upstream sequence
agggttagggttgggttagggttggggttggggttggggttggggttggggttgggttagggttagggttagggttagggttagggttagggttagggtt
Downstream sequence
ATGTAAGCCAGCTTTCTCCCAACTTTCACTGTTATTGCCAGAAAAGTGTTAAAATTTGAAAAAATAATCATACAAGTATTAGAATACTTTGAAAATGTAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate