HFM1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003141
Fusion event
HBV-HFM1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
91853008/91387451 (Hg38)
End
91853008/91387451 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
HFM1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-218-5p ; hsa-mir-2681-5p ; hsa-mir-4724-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-551b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/5029764; hsa-mir-11399/Downstream/2459381;
Nearest TSS
ENST00000473358/Upstream/34814; ENST00000497611/Downstream/17284;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/365201, chr1-CpG: 62/Downstream/16868
Upstream sequence
gccagttatccctgtggtaacttttctgacacctcctgcttaaaacccaaaaggtcagaaggatcgtgaggccccgctttcacggtctgtattcgtactg
Downstream sequence
aaaatcaagatcaagcgagcttttgcccttctgctccacgggaggtttctgtcctccctgagctcgccttaggacacctgcgttaccgtttgacaggtgt
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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