Basic Information
VIS ID
TVIS10003164
Fusion event
HBV-chr16 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
55419353/55385441 (Hg38)
End
55419353/55385441 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/4643064; hsa-mir-11401/Downstream/860079;
Nearest TSS
ENST00000527434/Upstream/51853; ENST00000568715/Downstream/4259;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/54039, chr16-CpG: 40/Downstream/93876
Nearby gene
IRX6(-54681) ; MMP2(+93728) ;
Upstream sequence
GAAAGAAGAAATAGCTAGACAAATCCTAAAGTCACCTCAGTGCTGTGGAACACACAGATCCCCCATTTCTATATGGGATTTACTGAATTGGAATTTCTGA
Downstream sequence
GGAAAGGGCTTAGGAATTCTGCCCTTTGAGAAAATGACCATGAGTATCTGGTAAACTTGGTAAAAACTTACTAAGGGAACCTTTGAACCCTTCAATTCCA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate