Basic Information
VIS ID
TVIS10003199
Fusion event
HBV-chr20 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr20
Cytoband
q12
Reference genome
GRCh37/hg19
Start
38716725/40088084 (Hg38)
End
38716725/40088084 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/1571452; hsa-mir-1-1/Downstream/1080939;
Nearest TSS
ENST00000382410/Upstream/56499; ENST00000445278/Downstream/32957;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/1037626, chr20-CpG: 92/Downstream/594654
Nearby gene
PRPF31(-79554) ; MAFB(+597763) ;
Nearest cancer related gene
MAFB(OG, +597763) ;
Upstream sequence
ATTCAAGTAATGCACTATTATATTATTTTGTAAAAATTCAAATATGTGGAATTTTCAGAGTCAAAAGTCAAATGTCTTTGACATCTTTGTCATTCCCTTT
Downstream sequence
ACCTACTCTCCTCATAGTCCCCTTCCTAGATTCAGGAATAACTAGTATCAATTTAGTGTGTATCCTCCCGTACCTTTTTCTACGTTTTTAGATACATAAA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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