Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003200
Fusion event
HBV-MIER1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
Start
End
67452497/66986814 (Hg38)
Location type
UTR3
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-30e-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-580-3p ; hsa-mir-4324 ; hsa-mir-4251 ; hsa-mir-20b-3p ; hsa-mir-3137 ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-3686 ; hsa-mir-190a-3p ; hsa-mir-298 ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-922 ; hsa-mir-5586-5p ; hsa-mir-410-3p ; hsa-mir-5197-3p ; hsa-mir-450b-5p ; hsa-mir-4511 ; hsa-mir-4696
Nearest miRNA
hsa-mir-101-1/Upstream/358297; hsa-mir-11399/Downstream/1196704;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/56014, chr1-CpG: 59/Downstream/67048
Upstream sequence
AAAGTTTTGGGTGGAAGTGTTGAGAAGTATGAGTTTTTTGTTGTTTTTGTTTTACTTAAAACTTTTAATTTATCCAGAATGGCAGTAGCTTTAGCAAGCA
Downstream sequence
GATGGTCACAATCTGTTTTCTAAATCATTTTTTATTAAATGAATCCAAAGTATCCTAGCTCTTTGTCAAAGATGGTCTGTAGAAATGTTTTTAAAGATTA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.