LRRC28 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003202
Fusion event
HBV-LRRC28 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
99847272/99307067 (Hg38)
End
99847272/99307067 (Hg38)
Location type
Intronic
Target gene
LRRC28
miRNAs that regulate target gene
hsa-mir-34a-5p
Nearest miRNA
hsa-mir-10393/Upstream/522565; hsa-mir-1302-10/Downstream/2653392;
Nearest TSS
ENST00000557528/Upstream/20365; ENST00000558248/Downstream/13536;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/55230, chr15-CpG: 154/Downstream/258096
Upstream sequence
GAGGATTAGCCTGCTGCTTTTCTCCTTCAAGCCATTACGTGTTTCTTCAGCGTCTGCCATTCATTGTCAGAATGGGGCCAGCTGTTCACTCTGGTGATCT
Downstream sequence
TTGTTTAATTGCCATTAGACTGTATGTAAACACTGGGGGCAGGTAATTCTGAAGCATGTTTTCATTGAGAGAGAGAGTTTATCTCATCTTTTACTAGACT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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