Basic Information
VIS ID
TVIS10003224
Fusion event
HBV-chr18 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
33450975/35871012 (Hg38)
End
33450975/35871012 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA18A
Nearest miRNA
hsa-mir-1-2/Upstream/279206; hsa-mir-122/Downstream/33806;
Nearest TSS
ENST00000575820/Upstream/154642; ENST00000587719/Downstream/94828;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/288712, chr18-CpG: 53/Downstream/78953
Nearby gene
GALNT1(-159177) ; MIR187(+33806) ;
Nearest cancer related gene
MIR187(TSG, +33806) ;
Upstream sequence
atagtatctcagcatagttttgacttgaattttttaaattatgagggagcttgaacattttttgtgtgtgaaatgtctgttcatattttttatccatttt
Downstream sequence
actcttgggttctttcgtcacttaaccttcaattaactccttagctatgacatatgttgcaaatattttctgcaagtttgccattcattgtttaactttg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate