Basic Information
VIS ID
TVIS10003232
Fusion event
HBV-LOC105370019 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
q24.23
Reference genome
GRCh37/hg19
Start
119320260/118882455 (Hg38)
End
119320260/118882455 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12E ; FRA12C
Target gene
LOC105370019
Nearest miRNA
hsa-let-7i/Upstream/2454137; hsa-mir-1178/Downstream/831179;
Nearest TSS
ENST00000382841/Upstream/48919; ENST00000545224/Downstream/26475;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/107867, chr12-CpG: 19/Downstream/98331
Nearby gene
SUDS3(-464420) ; SRRM4(+99040) ;
Upstream sequence
gtcactcaggctggagtgcagaggcatgatcttggctcactgcagcctccgcctcgtgggctcaagcaatcctcctgcctcagcctcccaaagtgctggg
Downstream sequence
actacaggtgtgaactactgtgcccagcCACCCAttttcacttttttaataccatcctttgatgcatgacagtttttaattttcatgttcaatttactta
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate