VISDB Viral Integration Site DataBase

VIS ID

TVIS10003245

Fusion event

HBV-PDGFRA integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr4

Cytoband

q12

Reference genome

Start

End

55089508/54223341 (Hg38)

Location type

Promoter

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-34a-5p ; hsa-mir-140-5p ; hsa-mir-26b-5p ; hsa-mir-34c-5p ; hsa-mir-130a-3p ; hsa-mir-143-3p ; hsa-mir-181a-5p ; hsa-mir-630 ; hsa-mir-130b-3p ; hsa-mir-218-5p ; hsa-mir-146b-5p ; hsa-mir-1910-3p ; hsa-mir-6511a-5p ; hsa-mir-29b-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-139-3p ; hsa-mir-298 ; hsa-mir-1827 ; hsa-mir-6746-5p ; hsa-mir-483-5p ; hsa-mir-4668-5p ; hsa-mir-544a ; hsa-mir-2276-3p ; hsa-mir-4772-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-455-3p ; hsa-mir-4719 ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-8485 ; hsa-mir-129-5p ; hsa-mir-6885-3p ; hsa-mir-628-5p ; hsa-mir-8075 ; hsa-mir-6778-5p ; hsa-mir-1233-5p

Nearest miRNA

hsa-mir-12113/Upstream/1510594; hsa-mir-1243/Downstream/6699278;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/113306, chr4-CpG: 26/Downstream/3453

Nearest cancer related gene

PDGFRA(OG, No orient, 0)

Upstream sequence

atttttatttttatgaatttatgcttatattcattttatatttagttttcttttctttctttctttttttttttttttgagatggagtttccctcttgtt

Downstream sequence

gtcaggctggtctccaactcctgacctcaagtgatccgcctgcctcagcctcccaaagcgctgggattacaggcatgagccaccatgcccggcccatcct