Basic Information
VIS ID
TVIS10003246
Fusion event
HBV-MIR548AZ integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
64878429/64411711 (Hg38)
End
64878429/64411711 (Hg38)
Location type
ncRNA_intronic
Fragile sites / regions
FRA14B
Target gene
MIR548AZ
Nearest miRNA
hsa-mir-208a/Upstream/316586; hsa-mir-1185-1/Downstream/373915;
Nearest TSS
ENST00000550708/Upstream/22984; ENST00000554057/Downstream/7492;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/23405, chr14-CpG: 62/Downstream/53450
Upstream sequence
acagatggccggacgcggtggctcacgccagtaatcccagcactttgggaggccgaggcgggcggatcacctgaggtcgggagttttagaccagcctaag
Downstream sequence
aaacatggagaaaccccatctctactaaaaatacaaaaaattagctgggtgtggtggcgcatgcctgtaatcccagctactcgggaggctgaggcaggag
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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