Basic Information
VIS ID
TVIS10003248
Fusion event
HBV-chr7 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr7
Cytoband
q31.33
Reference genome
GRCh37/hg19
Start
125390972/125750918 (Hg38)
End
125390972/125750918 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/8730599; hsa-mir-10399/Downstream/1307170;
Nearest TSS
ENST00000635602/Upstream/312696; ENST00000411856/Downstream/166953;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/820773, chr7-CpG: 237/Downstream/1500328
Nearby gene
PRPF31(-371597) ; GRM8(+687680) ;
Upstream sequence
AAATCAGCTTCGTGAGGTACGTCTTCAGTCTTAAGTCAGATTAGAAGATTATGTGAAGTAATTAACACTTAACATTGATTTAATGGTAGCTTCCACATGA
Downstream sequence
ATGTTCATTGTTATTTAAAATATTAAAAATCCTTGTGCTTCAGAATAACTGAGTGCATCTATATTTTGATTTGATGTTAAGAATATAATAAGAAATAGAT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate