UNC13B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003257
Fusion event
HBV-UNC13B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
35381884/35381887 (Hg38)
End
35381884/35381887 (Hg38)
Location type
Intronic
Target gene
UNC13B
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-221-3p ; hsa-mir-92a-3p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-101-2/Upstream/1913952; hsa-let-7a-1/Downstream/226207;
Nearest TSS
ENST00000422679/Upstream/40057; ENST00000481299/Downstream/14651;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/219475, chr9-CpG: 89/Downstream/107820
Upstream sequence
ctcctattcaacatagtgttggaagttctggccagggcaatcaggcaggagaaagaaataaagggtattcagttaggagaagaggaagtcaaattgtccc
Downstream sequence
TGTAGAAAAAGAATGTTGTAACTCACAGAAAAGGTATTTCTGTCTGCCTCAGAGTTGAGGGAACTCTGCAGGGAAAGAGGCATGTGAGAGTATGCAAGGA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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