Basic Information
VIS ID
TVIS10003267
Fusion event
HBV-chr9 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr9
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
35975460/35975463 (Hg38)
End
35975460/35975463 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/242468; hsa-let-7a-1/Downstream/848076;
Nearest TSS
ENST00000422679/Upstream/17309; ENST00000475774/Downstream/60970;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/3014, chr9-CpG: 73/Downstream/61338
Nearby gene
OR2S2(-17309) ; RECK(+61450) ;
Nearest cancer related gene
RECK(TSG, +61450) ;
Upstream sequence
AGGAGCCACAGtgtaagagatcgatcaggttgttgtgggaatcaggagactggagagattggtaggtgaaacagaaggatttttattgagtgcactcaga
Downstream sequence
tttattctttgagttattccgctccaaggtttgtttagttcttttttatgaactctttctctttgttgaatttctcattgtgatcatgaattgtttttct
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate