APLNR _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003273
Fusion event
HBV-APLNR integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
57001420/57233946 (Hg38)
End
57001420/57233946 (Hg38)
Location type
UTR3
Target gene
APLNR
miRNAs that regulate target gene
hsa-mir-10b-5p ; hsa-mir-16-5p
Nearest miRNA
hsa-mir-129-2/Upstream/489965; hsa-let-7a-2/Downstream/407252;
Nearest TSS
ENST00000527297/Upstream/52199; ENST00000534162/Downstream/3255;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1359302, chr11-CpG: 78/Downstream/90451
Upstream sequence
GAGGAGGTGACTCTGTGAAAGATGCTATCTTAAGATGGGGAGACTAGGCTGTGAGGAGCCCCTTCCCCTCTCCTCCTCCCTCTGCCCCCAGAGCTGGCGT
Downstream sequence
CATTCCAGGGAGGGTCAAGATGTCCATTCACATCAAGCTGGGCTTTTCTTATCTCCATCGCTCATGTCTTGTCCTTCACTTTCATAGTCCTCCAAGAACA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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