Basic Information
VIS ID
TVIS10003284
Fusion event
HBV-FGF4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q13.3
Reference genome
End
69598033/69783265 (Hg38)
Location type
Promoter
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10392/Upstream/700007; hsa-let-7a-2/Downstream/500690;
Nearest cancer related gene
FGF4(OG, No orient, 0)
Upstream sequence
GGACAAGGGCTCAGAGGGATAAGGATAATCTCTGGTACATTTTAACTATGAATGATTTAAAATACTCTTACTCTTTTTTGTTGTTCTTGttcttggtttt
Downstream sequence
ttttttttttttcttttgagacagggtcccactctgttacaggctggagtgcagtgaggcaatcatcgctcactgaagcctcaaactcctgggctcaagg
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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