Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003293
Fusion event
HBV-GRAMD1B integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
q24.1
Reference genome
End
123294165/123423457 (Hg38)
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-1277-5p ; hsa-mir-3686 ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-601 ; hsa-mir-4778-5p ; hsa-mir-4742-3p ; hsa-mir-8076 ; hsa-mir-5011-5p ; hsa-mir-6873-3p ; hsa-mir-4436b-5p ; hsa-mir-6509-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-99b-3p ; hsa-mir-99a-3p ; hsa-mir-2861 ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-4279 ; hsa-mir-6881-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-2116-3p ; hsa-mir-877-3p ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-1227-5p ; hsa-mir-128-1-5p ; hsa-mir-128-2-5p ; hsa-mir-2278 ; hsa-mir-4640-5p ; hsa-mir-4726-5p ; hsa-mir-4786-5p ; hsa-mir-6165 ; hsa-mir-6501-3p ; hsa-mir-6762-5p ; hsa-mir-6845-5p
Nearest miRNA
hsa-let-7a-2/Upstream/41945; hsa-mir-3167/Downstream/3565001;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/64693, chr11-CpG: 90/Downstream/6884
Upstream sequence
tcttctctctctcctTTTGCTCCCACTCCAACCACAAGTAACTTttcacagtctaactctaggcattagaaggatgtttaacacttagtagatgctcaaa
Downstream sequence
aactatttgaaaatagatgtccctcattctttttgctgactaatttctggaaagggcagtctaatcttgcagcttccattaattcattccctaactactc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.