Basic Information
VIS ID
TVIS10003296
Fusion event
HBV-OR14I1 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
GRCh37/hg19
Start
248851906/248688605 (Hg38)
End
248851906/248688605 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA1I
Target gene
OR14I1
Nearest miRNA
hsa-mir-101-1/Upstream/1486545; hsa-mir-3124/Downstream/137772;
Nearest TSS
ENST00000473358/Upstream/6301; ENST00000515369/Downstream/56674;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/751181, chr1-CpG: 49/Downstream/3124
Upstream sequence
TAACTAAAATACTAAGTGGGTGGAACCCACTGAAGACTAGAACAAATATTTTGTGTGCCTGACTCACCATGGTTACTTCTAATCTTGCTCTATAATCACA
Downstream sequence
GACTGGTACAACTTTTCTCTCCTGTTTTGTTTTCAAGATTGCAAGACTGAATAATATTTCCCCCCACCCACCAGAAAGAGTTTGGGGCATAGCAAAGATC
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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