Basic Information
VIS ID
TVIS10003316
Fusion event
HBV-MLIP integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
53914188/54049390 (Hg38)
End
53914188/54049390 (Hg38)
Location type
Intronic
Target gene
MLIP
Nearest miRNA
hsa-mir-10398/Upstream/772319; hsa-mir-10524/Downstream/3340742;
Nearest TSS
ENST00000381078/Upstream/1796; ENST00000460844/Downstream/13950;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/253216, chr6-CpG: 74/Downstream/796965
Upstream sequence
ttgcagtgagcaagatcactccactgcactccagcctggcgacagagcgagactccgtctcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaGTC
Downstream sequence
CTAGTGTCATGAGTAAGTCTTGGTGTCACTTATTGCTGGTTCGTTATGAAGCTGCAGAAATACTGACACAAATGCTAGATTGATGCTGATGGTACTTGTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate