NKAIN2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003326
Fusion event
HBV-NKAIN2 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr6
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
124808257/124487111 (Hg38)
End
124808257/124487111 (Hg38)
Location type
Intronic
Target gene
NKAIN2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10398/Upstream/4471854; hsa-mir-1202/Downstream/1997520;
Nearest TSS
ENST00000381078/Upstream/204107; ENST00000640160/Downstream/331288;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/682947, chr6-CpG: 128/Downstream/474867
Upstream sequence
gcgacagagcgagactccgtctcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaGTCAGGATGTCCTAACTGGTTTATTGGCTTCAAGGTCAATC
Downstream sequence
AATGTCCATTTTCATTAATAATCAGTATTTTTGGTCAGTGTTCCCAGAGTTGTCTAAATTTCTTTATATATCTAGATGCTGTGCTTTCAATGATTCTGTT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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