CDH18 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003330
Fusion event
HBV-CDH18 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr5
Cytoband
p14.3
Reference genome
GRCh37/hg19
Start
19908649/19908540 (Hg38)
End
19908649/19908540 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5E
Target gene
CDH18
miRNAs that regulate target gene
hsa-let-7e-5p
Nearest miRNA
hsa-mir-10397/Upstream/2752548; hsa-mir-103a-1/Downstream/12027562;
Nearest TSS
ENST00000502646/Upstream/22268; ENST00000513573/Downstream/79645;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2252926, chr5-CpG: 45/Downstream/396913
Upstream sequence
AAAGTTACATATTTGGATTACATTTCCATTAATTAAAACCTTATTAAAATAATATGTAATTTTTTTCTACCTAGTGTTCTATATTCTTTCATGTTTTTGA
Downstream sequence
TATAAACTTTTCTTCCTGGGAAGTGGGAGATATTGAACTGTTAGAAAAATGTTTTAGAATTTATTCATCTTTTTCCAGGTTTTCACAACTATTCCTTATA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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