PRPF31 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003332
Fusion event
HBV-PRPF31 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
65464355/67797118 (Hg38)
End
65464355/67797118 (Hg38)
Location type
ncRNA_intronic
Fragile sites / regions
FRA18C
Target gene
PRPF31
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-1-2/Upstream/715432; hsa-mir-548av/Downstream/5056203;
Nearest TSS
ENST00000575820/Upstream/121040; ENST00000580622/Downstream/17704;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/280382, chr18-CpG: 67/Downstream/917579
Upstream sequence
TGAGGTTTCTAATAGATGTTTTCACTAGGAGTGTTTAATTCTCCTGTGCATCCTTGTGAGGCAAAGTGAACAAACACCATTACCTGACGTTACCATCTTC
Downstream sequence
TGGGGCAGTTGGATTTAACACTTTACTCTGAGATTCTCTATGTTCATTTTCTATTAGTGACTGTCTCCTCTACATATCATATCTCTAAGTTATTATGACA
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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