VISDB Viral Integration Site DataBase

VIS ID

TVIS10003346

Fusion event

HBV-TP53 integration

Validated

No

Detection method

HIVID

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

7578646/7675328 (Hg38)

Location type

UTR5

Target gene

miRNAs that regulate target gene

hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-25-3p ; hsa-mir-30d-5p ; hsa-mir-1285-3p ; hsa-mir-612 ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-221-3p ; hsa-mir-222-3p ; hsa-mir-214-3p ; hsa-mir-10b-5p ; hsa-mir-34a-5p ; hsa-mir-608 ; hsa-mir-605-5p ; hsa-mir-504-5p ; hsa-mir-485-5p ; hsa-mir-27a-3p ; hsa-mir-454-3p ; hsa-mir-324-5p ; hsa-mir-150-5p ; hsa-mir-375 ; hsa-mir-200a-3p ; hsa-mir-491-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30e-5p ; hsa-mir-19b-3p ; hsa-mir-92a-2-5p ; hsa-mir-92a-1-5p ; hsa-mir-20a-5p ; hsa-mir-18a-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7150 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-7110-5p ; hsa-mir-4651 ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-6825-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-6731-5p ; hsa-mir-8085 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-1273f ; hsa-mir-6760-5p ; hsa-mir-5197-5p ; hsa-mir-2110 ; hsa-mir-4531 ; hsa-mir-937-5p ; hsa-mir-223-3p ; hsa-mir-4697-3p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-5702 ; hsa-mir-4795-5p ; hsa-mir-4682 ; hsa-mir-194-3p ; hsa-mir-5693 ; hsa-mir-622 ; hsa-mir-4650-5p ; hsa-mir-1972 ; hsa-mir-1296-3p ; hsa-mir-513b-3p ; hsa-mir-6749-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-4286 ; hsa-mir-5196-3p ; hsa-mir-5003-5p ; hsa-mir-3065-5p ; hsa-mir-3529-3p ; hsa-mir-3165 ; hsa-mir-6880-5p ; hsa-mir-8071 ; hsa-mir-6882-5p ; hsa-mir-1264 ; hsa-mir-19a-3p ; hsa-mir-377-3p ; hsa-mir-300 ; hsa-mir-663a ; hsa-mir-1228-3p ; hsa-mir-151a-5p ; hsa-mir-26a-1-3p ; hsa-mir-28-5p ; hsa-mir-125b-1-3p ; hsa-mir-518c-3p ; hsa-mir-638 ; hsa-mir-28-3p ; hsa-mir-24-3p ; hsa-mir-155-3p ; hsa-mir-150-3p ; hsa-mir-214-5p ; hsa-mir-1225-3p ; hsa-mir-1247-3p ; hsa-mir-330-3p ; hsa-mir-4276 ; hsa-mir-505-5p ; hsa-mir-5587-3p

Nearest miRNA

hsa-mir-1253/Upstream/451949; hsa-mir-10226/Downstream/412728;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/23308, chr17-CpG: 23/Downstream/10644

Nearest cancer related gene

TP53(TSG, No orient, 0)

Upstream sequence

GGGGAGTACTGTAGGAAGAGGAAGGAGACAGAGTTGAAAGTCAGGGCACAAGTGAACAGATAAAGCAACTGGAAGACGGCAGCAAAGAAACAAACATGCG

Downstream sequence

TAAGCACCTCCTGCAACCCACTAGCGAGCTAGAGAGAGTTGGCGTCTACACCTCAGGAGCttttcttttttttttttttttttgagatagggtcttgctc