SWAP70 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003355
Fusion event
HBV-SWAP70 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
9681486/9659939 (Hg38)
End
9681486/9659939 (Hg38)
Location type
Promoter
Target gene
SWAP70
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-145-5p ; hsa-mir-23c ; hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-130a-5p ; hsa-mir-4637 ; hsa-mir-4445-5p ; hsa-mir-186-3p ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a
Nearest miRNA
hsa-mir-210/Upstream/569560; hsa-let-7a-2/Downstream/848331;
Nearest TSS
ENST00000527297/Upstream/73225; ENST00000531814/Downstream/4138;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/45421, chr11-CpG: 37/Downstream/4146
Nearest cancer related gene
SWAP70(OG, No orient, 0)
Upstream sequence
tcttacctgctccttccaaacttacacgaaattcttctgtagtgaatcctatcctggatccacattgggaacggacatttgaggaactagatttcaactt
Downstream sequence
acctaattgacacagtacaaaCATCAGTGactgtcagataccatgatgctgatgctgtgtcttatacatactaccctctcatttaaacttcataccagtc
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate