CACNA2D4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10003359
Fusion event
HBV-CACNA2D4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
2016917/1907751 (Hg38)
End
2016917/1907751 (Hg38)
Location type
Intronic
Target gene
CACNA2D4
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-203b-3p ; hsa-mir-7158-3p
Nearest miRNA
hsa-mir-3649/Upstream/247371; hsa-let-7i/Downstream/5055948;
Nearest TSS
ENST00000382841/Upstream/22872; ENST00000544163/Downstream/7476;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/42478, chr12-CpG: 53/Downstream/216
Upstream sequence
GGCGTGTCTGGTGGGCGTGTCTGGTAAGCGTGCCTGGTGGGTGTGCCTGGTGGGCGTGTCTGGTGGACGGCCTGGTGGGCGTGCCTGGTGGGCGTGTCTG
Downstream sequence
GTGGGTGTGTCTGGTGGGCCAGCCTGGTGAGTATGCCTGGTGGGTGTGCCTGGTGGGCGTGTCTGGTGGGTGTGCTAGGTGGGCGTGCCTGGTGAGTGTG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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