Basic Information
VIS ID
TVIS10003365
Fusion event
HBV-MIR3681HG integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
12420980/12280854 (Hg38)
End
12420980/12280854 (Hg38)
Location type
ncRNA_intronic
Target gene
MIR3681HG
Nearest miRNA
hsa-mir-3681/Upstream/81653; hsa-mir-10b/Downstream/456513;
Nearest TSS
ENST00000437798/Upstream/174270; ENST00000412606/Downstream/33463;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/495727, chr2-CpG: 204/Downstream/435645
Upstream sequence
CATTCATTGACCCTTTCAGTAATTATTTAGCATCTTATGTGACGGCACCATGCCAGCTGAGAAAATGCAGAGAGCCCACTGTCAAATGTTGGAGATGGGG
Downstream sequence
CAGTCACCAGTGTTGGCAGCACACAGAGGAAGTACATGCCATGGTAGAATTAGGTCCAGGAACCATGAGAATCTAGAGGACAGGCTCCCAAAACCGGCCG
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
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