Basic Information
VIS ID
TVIS10003371
Fusion event
HBV-chr4 integration
Validated
No
Detection method
HIVID
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27703150
Virus Sequence
Virus name
HBV
Reference genome
AF090842.1;AB033554.1;AB014381.1;M32138.1;AB032431.1;AB036910.1;AB064310;AY090454.1
Host Sequence
Chromosome
chr4
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
31581363/31579741 (Hg38)
End
31581363/31579741 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA4D
Nearest miRNA
hsa-mir-12113/Upstream/2760073; hsa-mir-1243/Downstream/4846625;
Nearest TSS
ENST00000502981/Upstream/73075; ENST00000513211/Downstream/417656;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/856521, chr4-CpG: 100/Downstream/4664268
Nearby gene
PCDH7(-432940) ;
Upstream sequence
agtgacagtttctgttggcttattttattttatttttaaatgagccattctttcctgtttctttggatgccttataatttttttttgttgaaaattagac
Downstream sequence
TAGGGCTGGGAAGTTGTGAAGCTAAGATTGGGAAAGACACCTAGCATTGAATCTAAGGGACTGTTTCGATCCCCAAATATTGCTCTGTTTATCACGAACT
Reference
Zhao, L. H., et al.Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma. Nat Commun ,2016,7: 12992.
Curate